The Dr. Dhani Ram Baruah Heart Institute & Research Centre has officially launched its most ambitious research program to date — the Heart City Genomic Mapping Initiative — aimed at revolutionizing the diagnosis and treatment of complex diseases through precision medicine.
A New Era of Personalized Healthcare
The initiative focuses on total human genomic mapping combined with miRNA profiling, enabling physicians to detect disease at the molecular level and personalize treatment protocols for each individual.
By decoding genetic patterns specific to Indian and indigenous populations, this project seeks to bridge the gap between global research and local healthcare needs.
Objectives of the Initiative
- Map Genomic Sequences of thousands of patients across Northeast India
- Identify Gene Mutations linked to chronic and rare diseases
- Analyze miRNA Expression to understand disease triggers and progression
- Develop Personalized Therapies based on genetic predisposition
- Create a National Genetic Database for future drug development and clinical trials
Diseases in Focus
The genomic data will initially target conditions such as:
- Coronary Artery Disease
- Pancreatic Cancer
- Systemic Lupus Erythematosus (SLE)
- Takayasu Arteritis
- Moyamoya Disease
- Baruah Syndrome
- HIV/AIDS
This will support early detection and custom treatment regimens, reducing trial-and-error in clinical care and increasing success rates.
Technological Edge
Heart City is one of the few centers globally to integrate high-throughput genome sequencing, siRNA gene therapy, and clinical xenotransplantation research under one roof.
Using in-house tools developed by Dr. Baruah — including Combat Genes and ASA (Antigen Suppression Agent) — the center aims to translate genetic data directly into actionable treatments.
Global Collaboration
The initiative has already attracted interest from international partners in genomics and biotech. Discussions are underway with labs in Singapore, Germany, and the U.S. to share data, co-publish findings, and jointly develop targeted therapies for rare genetic conditions.
Dr. Baruah’s Vision
“This is not just about collecting genetic data. It’s about rewriting the way we approach medicine — from treating symptoms to correcting root causes at the genetic level,”
says Dr. Dhani Ram Baruah, who leads the project with a team of molecular biologists, bioinformaticians, and cardiac specialists.
Add a Comment