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The Beginning of

Our Story

Dr. Dhani Ram Baruah’s journey began not in the halls of conformity, but at the crossroads of innovation and audacity. Challenging medical orthodoxy, he envisioned a future where human lives could be saved through revolutionary breakthroughs in xenotransplantation and genetic engineering.

In the early 1990s, when organ shortages claimed countless lives, Dr. Baruah dared to ask: What if we could bridge the species barrier? His relentless pursuit of answers laid the foundation for a lifetime of research that would ignite global conversations, stir scientific controversies, and inspire the next generation of boundary-pushing physicians.

This is not just a story of medical progress—it’s a story of vision, courage, and a belief that tomorrow’s science begins with today’s questions.

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Dr Dhaniram Baruah

Director
Years of Expertise
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Open‑Heart Surgeries
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Patents Filed
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Successful Pig‑to‑Human Heart Transplant
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Innovations and Contributions

  • Baruah siRNA & Combat Genes
    Developed a plant‑derived siRNA platform from Himalayan medicinal plants, leading to 12 patented “Combat Genes” with potential applications against Cancer and HIV/AIDS.

  • Artificial Heart Technologies
    Invented multiple next‑generation heart valves—including the Zirconium Bileaflet Mechanical Valve and Stented/​Stentless Pericardial Trileaflet Valves—plus the fully implantable biological “Baruah Heart 21.”

  • Xenotransplantation Breakthroughs
    Pioneered the first clinical pig‑to‑human heart transplant (1996–97) using his Antigen Suppression Agent (ASA) to prevent hyperacute rejection, and developed a pig‑lung Biological Oxygenator and in‑vivo pig‑to‑human blood transfusion protocols.

  • Genomic & Regenerative Research
    First to perform total human genomic mapping with miRNA profiling in diseased states, laying groundwork for precision gene therapies.

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Key Milestones and Achievements

    • 1987 – Zirconium Bileaflet Mechanical Heart Valve; Anticalcification Agent; Stented Trileaflet Pericardial Valve

    • 1991–94 – Pericardial Coronary Bio‑Graft; Stentless Bileaflet Mitral Valve; Tricuspid Pericardial Valve; Aortic Valve Conduits; “Baruah Heart 21”

    • 1996 – Founded Dr. Dhani Ram Baruah Heart Institute & Research Centre (first open‑heart surgery center in North‑East India)

    • 1996–97 – First successful clinical xenotransplantation (pig heart) using ASA

    • 1999–2000 – In‑vivo pig‑to‑human blood transfusion studies analyzed via Scanning Electron Microscopy

Education and Credentials

      • HSLC – Dakshinpat HS School, Assam

      • HS & BSc – Nowgong College, Assam

      • MBBS – Dibrugarh Medical College, Assam

      • FRCS (Cardiac Surgery) – Royal College of Surgeons of England, London

      • MD – University of Glasgow, Scotland

      • Fellow – Royal College of Surgeons & Physicians in Cardiac Surgery, Glasgow

Medical Career

        • Profession – Cardiac Surgeon, Genetic Engineer, Medical Innovator

        • Sub‑Specialties – Cardiothoracic Surgery · Heart & Lung Transplantation · Regenerative Therapies

        • Institutions – Dr. Dhani Ram Baruah Heart Institute & Research Centre; University of Maryland Medical Center; Various UK Cardiac Centers

        • Global Impact – Over 5,000 open‑heart surgeries performed; led pioneering xenotransplantation and genomic medicine programs worldwide

Our Team

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Rose Doe

Periodontist
A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my
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Jin Zhao

Dental Hygienist
A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my
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Mark White

General Dentist
A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my
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John Smith

Orthodontist
A wonderful serenity has taken possession of my entire soul, like these sweet mornings of spring which I enjoy with my